Outcome of cranial surgery in Nigerian patients with hemoglobinopathies: A retrospective study.

Autor:	Badejo OA; Department of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria., Idowu OK; Department of Anaesthesia, College of Medicine, University of Ibadan, Ibadan, Nigeria., Balogun JA; Department of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria., Shokunbi WA; Department of Haematology, College of Medicine, University of Ibadan, Ibadan, Nigeria., Amanor-Boadu SD; Department of Anaesthesia, College of Medicine, University of Ibadan, Ibadan, Nigeria., Shokunbi MT; Department of Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Jazyk:	angličtina
Zdroj:	Surgical neurology international [Surg Neurol Int] 2019 Feb 06; Vol. 10, pp. 16. Date of Electronic Publication: 2019 Feb 06 (Print Publication: 2019).
DOI:	10.4103/sni.sni_180_18
Abstrakt:	Background: Surgical intervention in patients with hemoglobinopathies has been extensively reviewed in the literature, but information on the outcome of cranial surgery in this patient population in sub-Saharan Africa is limited. Methods: This is a retrospective study of patients with hemoglobinopathies, who underwent brain surgery in our facility. The review covered a 5-year period. We examined patient- and surgery-related variables and described the surgical complications as well as the 60-day mortality. Results: A total of nine procedures (eight under general anesthesia and one under local anesthesia) were performed on seven patients with hemoglobinopathy during the study period. Eight (88.9%) of these were done in female patients and one (11.1%) in a male patient. Six (66.7%) were performed in patients with no previous history of blood transfusion. Hb SC accounted for five (55.6%), Hb SS for three (33.3%), and Hb CC for one (11.1%) procedure, respectively. Three (33.3%) of these procedures were brain tumor-related, three (33.3%) trauma-related, one (11.1%) cosmetic, one (11.1%) vascular, and one for a postoperative complication. Only one (11.1%) procedure was associated with preoperative blood transfusion, whereas there was a need for blood transfusion following five (55.6%) of the procedures. There was a mortality rate of 11.1% (1 case). Other complications were recorded after three (33.3%) of the procedures and none with five (55.6%) of the procedures. Conclusion: Neurosurgery is possible and safe in patients with hemoglobin disorders. Adequate preoperative preparation, proper anesthetic techniques, meticulous surgery, and excellent postoperative care can help optimize outcome of surgical intervention in this patient population. Competing Interests: There are no conflicts of interest.
Databáze:	MEDLINE
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