Burden of varicella in Central and Eastern Europe: findings from a systematic literature review.

Autor:	Mészner Z; a Heim Pal National Paediatric Institute , Budapest , Hungary., Wysocki J; b Department of Preventive Medicine , Poznan University of Medical Sciences , Poznan , Poland., Richter D; c Department of Paediatrics , University Hospital Centre , Zagreb , Croatia., Zavadska D; d Department of Paediatrics , Riga Stradins University , Riga , Latvia., Ivaskeviciene I; e Clinic of Children's Diseases, Institute of Clinical Medicine, Faculty of Medicine , Vilnius University , Vilnius , Lithuania.; f Vilnius University Hospital Santaros Klinikos , Vilnius , Lithuania., Usonis V; e Clinic of Children's Diseases, Institute of Clinical Medicine, Faculty of Medicine , Vilnius University , Vilnius , Lithuania., Pokorn M; g Department of Infectious Diseases , University Medical Centre Ljubljana , Ljubljana , Slovenia., Mangarov A; h Hospital for Infectious Diseases , Medical University of Sofia , Sofia , Bulgaria., Jancoriene L; f Vilnius University Hospital Santaros Klinikos , Vilnius , Lithuania.; i Clinic of Infectious Diseases and Dermatovenerology, Institute of Clinical Medicine, Faculty of Medicine , Vilnius University , Vilnius , Lithuania., Man SC; j Mother and Child Care Department , University of Medicine and Pharmacy 'Iuliu Hațieganu' , Cluj-Napoca , Romania., Kristufkova Z; k Faculty of Public Health , Slovak Medical University , Bratislava , Slovakia., Jesenak M; l Jessenius Faculty of Medicine in Martin , Comenius University , Bratislava , Slovakia., Tešović G; m University Hospital for Infectious Diseases , University of Zagreb, School of Medicine , Zagreb , Croatia., Pluta J; n Global Medical Affairs , MSD Polska Sp. z. o.o ., Warsaw , Poland., Wolfson LJ; o Center for Observational and Real-World Evidence (CORE) , Merck & Co., Inc ., Kenilworth , NJ , USA.
Jazyk:	angličtina
Zdroj:	Expert review of vaccines [Expert Rev Vaccines] 2019 Mar; Vol. 18 (3), pp. 281-293. Date of Electronic Publication: 2019 Feb 27.
DOI:	10.1080/14760584.2019.1573145
Abstrakt:	Introduction: Vaccination against varicella rapidly reduces disease incidence, resulting in reductions in both individual burden and societal costs. Despite these benefits, there is no standardization of varicella immunization policies in Europe, including countries in Central and Eastern Europe (CEE). Areas Covered: This systematic literature review identified publications on the epidemiology of varicella, its associated health and economic burden, and vaccination strategies within the CEE region, defined as Albania, Bosnia-Herzegovina, Bulgaria, Croatia, Cyprus, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania, Serbia, Slovakia, and Slovenia. Twenty-six studies were identified from a search of PubMed, Embase®, and MEDLINE® biomedical literature databases, supplemented by gray literature and country-specific/global websites. Expert Commentary: Limited information exists in published studies on the burden of varicella in CEE. The wide variability in incidence rates between countries is likely explained by a lack of consistency in reporting systems. Funded universal varicella vaccination (UVV) in CEE is currently available only in Latvia as a one-dose schedule, but Hungary together with Latvia are introducing a two-dose strategy in 2019. For countries that do not provide UVV, introduction of vaccination is predicted to provide substantial reductions in cases and rates of associated complications, with important economic benefits.
Databáze:	MEDLINE
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