Characterizing adolescents with heavy menstrual bleeding and generalized joint hypermobility.

Autor: Kendel NE; Pediatric Residency Program, Nationwide Children's Hospital/The Ohio State University, Ohio, Columbus., Haamid FW; Division of Adolescent Medicine, Nationwide Children's Hospital/The Ohio State University, Ohio, Columbus., Christian-Rancy M; Division of Pediatric Hematology/Oncology, Nationwide Children's Hospital/The Ohio State University, Ohio, Columbus., O'Brien SH; Division of Pediatric Hematology/Oncology, Nationwide Children's Hospital/The Ohio State University, Ohio, Columbus.
Jazyk: angličtina
Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2019 Jun; Vol. 66 (6), pp. e27675. Date of Electronic Publication: 2019 Feb 25.
DOI: 10.1002/pbc.27675
Abstrakt: Patients with generalized joint hypermobility (JHM) may experience excessive bruising/bleeding, with heavy menstrual bleeding (HMB) commonly reported. We performed a retrospective review of 30 adolescents seen in a Young Women's Hematology Clinic with both HMB and JHM. We found that (1) a significant delay (mean 36 months, range 5-72) occurred between menarche and referral to specialty care, (2) HMB had moderate to severe impact on school and physical activities in 60% of patients, and (3) most patients (68%) required escalation of their initial therapy. We suggest providers consider JHM as a risk factor for a more complex clinical course.
(© 2019 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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