Neurodevelopmental Outcomes of Very Low Birth Weight Infants at 18-24 Months, Corrected Gestational Age in a Tertiary Health Centre: A Prospective Cohort Study.

Autor:	Oommen SP; Developmental Pediatrics Unit, Christian Medical College, Vellore, Tamil Nadu, India., Santhanam S; Department of Neonatology, Christian Medical College, Vellore, Tamil Nadu, India., John H; Department of Neonatology, Christian Medical College, Vellore, Tamil Nadu, India., Roshan R; Developmental Pediatrics Unit, Christian Medical College, Vellore, Tamil Nadu, India., Swathi TO; Developmental Pediatrics Unit, Christian Medical College, Vellore, Tamil Nadu, India., Padankatti C; Developmental Pediatrics Unit, Christian Medical College, Vellore, Tamil Nadu, India., Grace H; Developmental Pediatrics Unit, Christian Medical College, Vellore, Tamil Nadu, India., Beulah R; Developmental Pediatrics Unit, Christian Medical College, Vellore, Tamil Nadu, India., Jana AK; Department of Neonatology, Christian Medical College, Vellore, Tamil Nadu, India., Kumar M; Department of Neonatology, Christian Medical College, Vellore, Tamil Nadu, India., Thomas N; Department of Neonatology, Christian Medical College, Vellore, Tamil Nadu, India., Yadav B; Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.
Jazyk:	angličtina
Zdroj:	Journal of tropical pediatrics [J Trop Pediatr] 2019 Dec 01; Vol. 65 (6), pp. 552-560.
DOI:	10.1093/tropej/fmz006
Abstrakt:	Objective: To determine the prevalence and risk factors for poor neurodevelopmental outcome in a cohort of very low birth weight (VLBW) infants. Subjects and Methods: Four hundred and twenty-two infants of a total of 643 VLBW survivors from a teaching hospital in South India were followed up to assess their neurodevelopmental outcomes. Results: Among the 422 children who completed the assessment, results of 359 children whose assessments were done between 18 and 24 months were analysed. Thirty-seven children (10.31%) had poor neurodevelopmental outcome, six children [1.67%] had cerebral palsy, one child had visual impairment and another had hearing impairment. Poor post-natal growth was independently associated with poor neurodevelopmental outcomes in the multivariate analysis (p = 0.045). Neonatal complications were not associated with the developmental outcome. Conclusion: Despite lower rates of neonatal complications compared with Western cohorts, significant proportion of VLBW infants had poor neurodevelopmental outcomes. Poor post-natal growth was an important determinant of the developmental outcome. (© The Author(s) [2019]. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
Databáze:	MEDLINE
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