| Autor: |
Revin VV; Federal State-Financed Academic Institution of Higher Education 'National Research Ogarev Mordovia State University', Saransk 430005, Russia., Gromova NV; Federal State-Financed Academic Institution of Higher Education 'National Research Ogarev Mordovia State University', Saransk 430005, Russia., Revina ES; Federal State-Financed Academic Institution of Higher Education 'National Research Ogarev Mordovia State University', Saransk 430005, Russia., Samonova AY; Federal State-Financed Academic Institution of Higher Education 'National Research Ogarev Mordovia State University', Saransk 430005, Russia., Tychkov AY; Federal State-Financed Academic Institution of Higher Education 'National Research Ogarev Mordovia State University', Saransk 430005, Russia., Bochkareva SS; Federal State-Financed Academic Institution of Higher Education 'National Research Ogarev Mordovia State University', Saransk 430005, Russia., Moskovkin AA; Federal State-Financed Academic Institution of Higher Education 'National Research Ogarev Mordovia State University', Saransk 430005, Russia., Kuzmenko TP; Federal State-Financed Academic Institution of Higher Education 'National Research Ogarev Mordovia State University', Saransk 430005, Russia. |
| Abstrakt: |
Using a wide range of different physical and chemical methods, it was found that the oxidative stress caused by addition of hydrogen peroxide to the incubation medium has a significant effect on the conformation of haematoporphyrin, influencing the oxygen-binding properties of haemoglobin in red blood cells. Morphofunctional characteristics of red blood cells change; in particular, we have observed the transformation of erythrocytes, their transition into echinocytes. In erythrocytes, in response to increased lipid peroxidation (LPO) antioxidant enzymes become active. The use of natural antioxidants ( β -carotene and resveratrol) works towards reducting the level of oxidative processes. Resveratrol has the greatest antioxidant effect. |
