Prostate Cancer Pulmonary Metastasis Presenting as a Ground-Glass Pulmonary Nodule on 68Ga-PSMA-11 PET/CT.

Autor: Lubin DJ; Ahmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology, Holden SB; Institute of Urologic Oncology, Department of Urology, Rettig MB; Institute of Urologic Oncology, Department of Urology, Reiter RE; Institute of Urologic Oncology, Department of Urology, King CR; Institute of Urologic Oncology, Department of Urology; Department of Radiation Oncology, Lee JM; Division of Thoracic Surgery, Department of Surgery, Wallace DW; Department of Pathology & Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, Calais J; Ahmanson Translational Theranostics Division, Department of Molecular & Medical Pharmacology; Institute of Urologic Oncology, Department of Urology
Jazyk: angličtina
Zdroj: Clinical nuclear medicine [Clin Nucl Med] 2019 May; Vol. 44 (5), pp. e353-e356.
DOI: 10.1097/RLU.0000000000002499
Abstrakt: Ga-prostate-specific membrane antigen 11 (PSMA) PET/CT imaging accurately depicts metastatic prostate adenocarcinoma (PCa). Pulmonary metastases of PCa are often overlooked on follow-up imaging in patients after initial treatment and following androgen deprivation therapy. Here we present a rare case of biopsy-proven PCa pulmonary metastasis with a ground-glass appearance. The increased PSMA expression and the evolving CT features of the solid component of the ground-glass nodule detected by PSMA PET/CT imaging led to surgical resection and PET/CT-guided therapy.
Databáze: MEDLINE