| Autor: |
Lee SJ; Department of Radiology, University of Michigan, Ann Arbor, MI 48109, USA. pjhscott@umich.edu., Brooks AF, Ichiishi N, Makaravage KJ, Mossine AV, Sanford MS, Scott PJH |
| Jazyk: |
angličtina |
| Zdroj: |
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2019 Mar 05; Vol. 55 (20), pp. 2976-2979. |
| DOI: |
10.1039/c9cc00641a |
| Abstrakt: |
This report describes a Pd-mediated C-H radiofluorination of 8-methylquinoline derivatives with no-carrier-added Ag[18F]F. To achieve this transformation, a new method was developed for the generation of Ag[18F]F using a sep-pak cartridge. The C-H radiofluorination was then optimized and applied to a series of substituted 8-methylquinoline derivatives. Finally, this method was fully automated using a radiochemistry synthesis module. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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