Association Between Patient and Physician Sex and Physician-Estimated Stroke and Bleeding Risks in Atrial Fibrillation.

Autor: Lee H; Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Tan MK; Canadian Heart Research Centre, Toronto, Ontario, Canada., Yan AT; Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Angaran P; Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Dorian P; Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Bucci C; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Gregoire JC; Université de Montréal, Institut de Cardiologie de Montréal, Montréal, Quebec, Canada., Bell AD; University of Toronto, Department of Family and Community Medicine, Toronto, Ontario, Canada., Green MS; University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Gross PL; Thrombosis and Atherosclerosis Research Institute, McMaster University, Juravinski Henderson Hospital, Hamilton, Ontario, Canada., Skanes A; Western University, London, Ontario, Canada., Kerr CR; St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Mitchell LB; Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary and Alberta Health Services, Calgary, Alberta, Canada., Cox JL; Dalhousie University, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia., Essebag V; McGill University Health Centre and Hôpital Sacré Coeur de Montréal, Montréal, Quebec, Canada., Heilbron B; St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Ramanathan K; St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Fournier C; Hôpital Notre-Dame, Université de Montréal, Montreal, Quebec, Canada., Wheeler BH; Calgary Foothills Primary Care Network, Calgary, Alberta, Canada., Lin PJ; Canadian Heart Research Centre, Toronto, Ontario, Canada., Berall M; University of Toronto, Department of Family and Community Medicine, Toronto, Ontario, Canada; Humber River Hospital, Toronto, Ontario, Canada., Langer A; Canadian Heart Research Centre, Toronto, Ontario, Canada., Goldin L; Canadian Heart Research Centre, Toronto, Ontario, Canada., Goodman SG; Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada; Canadian Heart Research Centre, Toronto, Ontario, Canada. Electronic address: goodmans@chrc.net.
Jazyk: angličtina
Zdroj: The Canadian journal of cardiology [Can J Cardiol] 2019 Feb; Vol. 35 (2), pp. 160-168. Date of Electronic Publication: 2018 Dec 03.
DOI: 10.1016/j.cjca.2018.11.023
Abstrakt: Background: Physicians treating nonvalvular atrial fibrillation (AF) assess stroke and bleeding risks when deciding on anticoagulation. The agreement between empirical and physician-estimated risks is unclear. Furthermore, the association between patient and physician sex and anticoagulation decision-making is uncertain.
Methods: We pooled data from 2 national primary care physician chart audit databases of patients with AF (Facilitating Review and Education to Optimize Stroke Prevention in Atrial Fibrillation and Coordinated National Network to Engage Physicians in the Care and Treatment of Patients with Atrial Fibrillation Chart Audit) with a combined 1035 physicians (133 female, 902 male) and 10,927 patients (4567 female and 6360 male).
Results: Male physicians underestimated stroke risk in female patients and overestimated risk in male patients. Female physicians estimated stroke risk well in female patients but underestimated the risk in male patients. Risk of bleeding was underestimated in all. Despite differences in risk assessment by physician and patient sex, > 90% of patients received anticoagulation across all subgroups. There was modest agreement between physician estimated and calculated (ie, CHADS 2 score) stroke risk: Kappa scores were 0.41 (0.35-0.47) for female physicians and 0.34 (0.32-0.36) for male physicians.
Conclusions: Our study is the first to examine the association between patient and physician sex influences and stroke and bleeding risk estimation in AF. Although there were differences in agreement between physician estimated stroke risk and calculated CHADS 2 scores, these differences were small and unlikely to affect clinical practice; further, despite any perceived differences in the accuracy of risk assessment by sex, most patients received anticoagulation.
(Copyright © 2018 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: