Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature.

Autor: Boucher JI; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605., Bolon DNA; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605., Tawfik DS; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 76100, Israel.
Jazyk: angličtina
Zdroj: Protein science : a publication of the Protein Society [Protein Sci] 2019 Mar; Vol. 28 (3), pp. 671.
DOI: 10.1002/pro.3476
Databáze: MEDLINE