Prenatal factors associated with fetal visceral adiposity.

Autor: Sena ASS; Instituto de Pesquisa Professor Joaquim Amorim Neto (IPESq), Campina Grande, PB, Brazil. Electronic address: ft.alinesena@hotmail.com., Souza ASR; Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Programa de Pós-graduação em Saúde Materno Infantil, Recife, PE, Brazil; Universidade Federal Pernambuco (UFPE), Departamento de Saúde Materno-Infantil, Recife, PE, Brazil; Universidade Católica de Pernambuco (Unicap), Centro de Ciências Biológicas e Saúde, Recife, PE, Brazil., Barros VO; Instituto de Pesquisa Professor Joaquim Amorim Neto (IPESq), Campina Grande, PB, Brazil; Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Programa de Pós-graduação em Saúde Materno Infantil, Recife, PE, Brazil., Lima MDCP; Instituto de Pesquisa Professor Joaquim Amorim Neto (IPESq), Campina Grande, PB, Brazil; Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Programa de Pós-graduação em Saúde Materno Infantil, Recife, PE, Brazil., Melo ASO; Instituto de Pesquisa Professor Joaquim Amorim Neto (IPESq), Campina Grande, PB, Brazil; Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Programa de Pós-graduação em Saúde Materno Infantil, Recife, PE, Brazil., Amorim MMR; Instituto de Pesquisa Professor Joaquim Amorim Neto (IPESq), Campina Grande, PB, Brazil; Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Programa de Pós-graduação em Saúde Materno Infantil, Recife, PE, Brazil; Universidade Federal de Campina Grande (UFCG), Departamento de Ginecologia e Obstetrícia, Campina Grande, PB, Brazil.
Jazyk: angličtina
Zdroj: Jornal de pediatria [J Pediatr (Rio J)] 2020 May - Jun; Vol. 96 (3), pp. 341-349. Date of Electronic Publication: 2019 Feb 10.
DOI: 10.1016/j.jped.2018.11.013
Abstrakt: Objective: To assess fetal visceral adiposity and associated factors during pregnancy.
Methods: Secondary analysis of prospective cohort data with 172 pairs (pregnant woman/fetus) treated at public health units. Anthropometric data, metabolic (glucose, glycated hemoglobin, insulin, insulin resistance, total cholesterol and fractions, triglycerides) measures, fetal biometry, and visceral and subcutaneous adiposity in the binomial (pregnant woman/fetus) were evaluated at the 16 th , 28 th and 36 th gestational weeks by ultrasonography. Pearson's correlation coefficient and multiple linear regression were used, with a significance level of 5%.
Results: At the 16 th week, the mean age of the pregnant women was 26.6±5.8 years and mean weight was 62.7±11.5kg; 47.0% had normal weight, 28.3% were overweight, 13.3% were underweight, and 11.2% were obese. At 36 weeks, 44.1% had inadequate gestational weight gain, 32.5% had adequate gestational weight gain, and 23.3% had excessive gestational weight gain. Fetal visceral adiposity at week 36 showed a positive correlation with maternal variables: weight (r=0.15) and body mass index (r=0.21) at the 16 th ; with weight (r=0.19), body mass index (r=0.24), and gestational weight gain (r=0.21) at the 28 th ; and with weight (r=0.22), body mass index (r=0.26), and gestational weight gain (r=0.21) at the 36 th week. After multiple linear regression, adiposity at the 28 th week remained associated with fetal variables: abdominal circumference (p<0.0001), head circumference (p=0.01), area (p<0.0001), and thigh circumference (p<0.001). At the 36 th week, adiposity remained associated with the abdominal circumference of the 28 th (p=0.02) and 36 th weeks (p<0.001).
Conclusion: Adiposity was positively correlated with the measurements of the pregnant woman. After the multivariate analysis, the persistence of the association occurred with the abdominal circumference, a central adiposity measurement with a higher metabolic risk.
(Copyright © 2019. Published by Elsevier Editora Ltda.)
Databáze: MEDLINE
Externí odkaz: