Effect of Early Breast Milk Nutrition on Serum Insulin-Like Growth Factor-1 in Preterm Infants.

Autor:	Alzaree FA; Department of Child Health, National Research Centre, Cairo, Egypt., AbuShady MM; Department of Child Health, National Research Centre, Cairo, Egypt., Atti MA; Department of Child Health, National Research Centre, Cairo, Egypt., Fathy GA; Department of Child Health, National Research Centre, Cairo, Egypt., Galal EM; Department of Child Health, National Research Centre, Cairo, Egypt., Ali A; Department of Child Health, National Research Centre, Cairo, Egypt., Elias TR; Department of Medical Biochemistry, Medical Research Division, National Research Centre, Cairo, Egypt.
Jazyk:	angličtina
Zdroj:	Open access Macedonian journal of medical sciences [Open Access Maced J Med Sci] 2019 Jan 12; Vol. 7 (1), pp. 77-81. Date of Electronic Publication: 2019 Jan 12 (Print Publication: 2019).
DOI:	10.3889/oamjms.2019.035
Abstrakt:	Background: Insulin-like growth factor 1 (IGF-1) is one of the essential intrauterine hormonal mediators of growth, and its serum values are often low after preterm delivery. Aim: To evaluate the influence of immediate breast milk feeding on serum IGF-1 in preterm newborns. Subjects and Methods: This prospective, observational cohort study included 60 premature infants born < 32 weeks of gestation, divided into group A and B regarding breastfeeding or formula feeding. Growth measurements were taken at birth. The standard deviation of each measurement was calculated. Serum IGF-I was measured one day postnatal and at a time equivalent to 40 weeks of gestation. Results: Significant higher level of mean serum IGF-1 was detected in group A than B at postnatal age equivalent to 40 weeks of gestation. In group A, the higher significant level was detected in mean serum IGF-1 at an age equivalent to 40 weeks of gestation than at birth (25.21 ± 6.69 and 20.13 ± 5.46 p < 0.05). Multiple linear regression analysis showed that high birth weight, increased age of gestation and breastfeeding were correlated to the elevated serum level of IGF-1 at a postnatal age corresponding to 40 weeks gestational age. Conclusion: Immediate breast milk feeding was accompanied by elevated IGF-1 in the serum of preterm infants.
Databáze:	MEDLINE
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