Gonococcal infection: An unresolved problem.

Autor: Barberá MJ; Unidad de ITS Vall d'Hebron-Drassanes, Servicio de Enfermedades Infecciosas, Hospital Universitario Vall d'Hebron, Barcelona, España; Vall d'Hebron Institut de Recerca, Barcelona, España; Universitat de Barcelona, Barcelona, España; GeITS de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC), Madrid, España., Serra-Pladevall J; Vall d'Hebron Institut de Recerca, Barcelona, España; GeITS de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC), Madrid, España; Servicio de Microbiología, Hospital Universitario Vall d'Hebron, Barcelona, España; Departamento de Genética y Microbiología, Universitat Autònoma de Barcelona, Barcelona, España. Electronic address: juserra@vhebron.net.
Jazyk: English; Spanish; Castilian
Zdroj: Enfermedades infecciosas y microbiologia clinica (English ed.) [Enferm Infecc Microbiol Clin (Engl Ed)] 2019 Aug - Sep; Vol. 37 (7), pp. 458-466. Date of Electronic Publication: 2019 Feb 04.
DOI: 10.1016/j.eimc.2018.12.008
Abstrakt: Gonococcal infection is a current public health problem worldwide, being the second most prevalent bacterial sexually transmitted infection. The etiologic agent is Neisseria gonorrhoeae, a gram-negative diplococcus, and mainly causes urethritis in men. In women up to 50% of infections can be asymptomatic. N. gonorrhoeae has a great ability to develop antibiotic resistance, so the last remaining therapeutic option are extended spectrum cephalosporins. Many guides recommend dual therapy with ceftriaxone and azithromycin, but in recent years the resistance to azithromycin is also increasing, so that dual treatment is being questioned by scientific societies.
(Copyright © 2019 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.)
Databáze: MEDLINE