Optimisation of birth weight and growth in the first 2 years favours an adult body composition which supports more physiological resting metabolic rates and cognitive function : Tanjungsari Cohort Study (TCS).

Autor:	Nugraha GI; Division of Biochemistry and Molecular Biology, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Sumedang, Indonesia., Ong PA; Department of Neurology, Hasan Sadikin General Hospital, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia. anam_ong@yahoo.com., Rachmi CN; Department of Public Health, Faculty of Medicine, Universitas Padjadjaran, Sumedang, Indonesia., Karyadi SHK; Division of Endocrinology, Department of Internal Medicine, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia., Alisjahbana A; Frontier for Health Foundation, Bandung, Indonesia.
Jazyk:	angličtina
Zdroj:	Asia Pacific journal of clinical nutrition [Asia Pac J Clin Nutr] 2019; Vol. 28 (Suppl 1), pp. S51-S62.
DOI:	10.6133/apjcn.201901_28(S1).0005
Abstrakt:	Background and Objectives: Resting metabolic rate and cognitive function may be associated with several factors, such as birth weight, growth, and fat-free mass in adulthood. The Tanjungsari Cohort Study (TCS) of 1988, to do with a maternal-child Risk Approach Strategy (RAS), provided the opportunity to determine the associations between birth weight, growth at 2 years, and body composition with adult resting metabolic rate and cognitive function. Methods and Study Design: In 2009 some 197 and, in 2017,144 of these representative participants from the TCS were assessed for energy intake, anthropometry, body composition, indirect calorimetry, and cognitive function in relation to low (ALBW, n=66) or normal (ANBW, n=78) birth weight. Associations were adjusted for basic demographic data. Results: Resting metabolic rate was positively associated with birth weight, body weight at 2 years of age, body mass index and fat free mass in adult life. Time to finish the Trail Making Test-A (TMT-A), a test of attention span, was significantly longer in the ALBW than the ANBW group (41.4±12.8 vs 37.8±15.6, p=0.005). In the ALBW group, weight catch-up improved TMT-A and logical memory test scores (29.5 vs 34.9.41, p=0.004; and 39.3 vs 29.4, p=0.04, respectively). Conclusions: Low birth weight was associated with poorer attention span in adult life; body weight gain at 2 years of age with better attention and memory function in adult life; a greater body mass index in adult life with better memory in adult life.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu