Physiology, Biliary
| Autor: | Dave HD; Tver State Medical University, Tver, Russian Federation, Al Obaidi NM; KAMC |
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| Jazyk: | angličtina |
| Zdroj: | 2022 Jan. |
| Abstrakt: | Bile is a unique alkaline secretion of the body. It is secreted from the hepatocytes and is further altered and refined by the epithelial cells lining the biliary tract. The gallbladder stores this fluid, where it gets concentrated and subsequently released into the digestive tract via the common bile duct. On receiving stimulation via the hormone cholecystokinin from the intestinal tract due to the presence of food in the intestinal lumen, the gallbladder contracts and secretes the bile into the duodenum.[1] The composition of bile is predominantly water with multiple dissolved substances, including cholesterol, amino acids, enzymes, vitamins, heavy metals, bile salts, bilirubin, phospholipids, and other constituents such as drugs and toxins.[1] The cells lining the intrahepatic and extrahepatic biliary ducts are collectively referred to as cholangiocytes. Their primary role is to alter and refine the contents of the hepatically synthesized bile via a complex mechanism controlled by a multitude of molecules, hormones, and neurotransmitters.[2] (Copyright © 2022, StatPearls Publishing LLC.) |
| Databáze: | MEDLINE |
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