Feasibility and safety of intraoperative BOLD functional MRI cerebrovascular reactivity to evaluate extracranial-to-intracranial bypass efficacy.

Autor: Muscas G; 1Department of Neurosurgery, University Hospital Zurich, University of Zurich, Switzerland.; 2Department of Neurosurgery, Careggi Hospital, University of Florence, Italy.; 3Clinical Neuroscience Center, University Hospital Zurich; and., Bas van Niftrik CH; 1Department of Neurosurgery, University Hospital Zurich, University of Zurich, Switzerland.; 3Clinical Neuroscience Center, University Hospital Zurich; and., Fierstra J; 1Department of Neurosurgery, University Hospital Zurich, University of Zurich, Switzerland.; 3Clinical Neuroscience Center, University Hospital Zurich; and., Piccirelli M; 3Clinical Neuroscience Center, University Hospital Zurich; and.; 4Department of Neuroradiology, University Hospital Zurich, University of Zurich, Switzerland; and., Sebök M; 1Department of Neurosurgery, University Hospital Zurich, University of Zurich, Switzerland.; 3Clinical Neuroscience Center, University Hospital Zurich; and., Burkhardt JK; 1Department of Neurosurgery, University Hospital Zurich, University of Zurich, Switzerland.; 5Department of Neurosurgery, Baylor College of Medicine Medical Center, Houston, Texas., Valavanis A; 3Clinical Neuroscience Center, University Hospital Zurich; and., Pangalu A; 3Clinical Neuroscience Center, University Hospital Zurich; and.; 4Department of Neuroradiology, University Hospital Zurich, University of Zurich, Switzerland; and., Regli L; 1Department of Neurosurgery, University Hospital Zurich, University of Zurich, Switzerland.; 3Clinical Neuroscience Center, University Hospital Zurich; and., Bozinov O; 1Department of Neurosurgery, University Hospital Zurich, University of Zurich, Switzerland.; 3Clinical Neuroscience Center, University Hospital Zurich; and.
Jazyk: angličtina
Zdroj: Neurosurgical focus [Neurosurg Focus] 2019 Feb 01; Vol. 46 (2), pp. E7.
DOI: 10.3171/2018.11.FOCUS18502
Abstrakt: Blood oxygenation level-dependent functional MRI cerebrovascular reactivity (BOLD-CVR) is a contemporary technique to assess brain tissue hemodynamic changes after extracranial- intracranial (EC-IC) bypass flow augmentation surgery. The authors conducted a preliminary study to investigate the feasibility and safety of intraoperative 3-T MRI BOLD-CVR after EC-IC bypass flow augmentation surgery. Five consecutive patients selected for EC-IC bypass revascularization underwent an intraoperative BOLD-CVR examination to assess early hemodynamic changes after revascularization and to confirm the safety of this technique. All patients had a normal postoperative course, and none of the patients exhibited complications or radiological alterations related to prolonged anesthesia time. In addition to intraoperative flow measurements of the bypass graft, BOLD-CVR maps added information on the hemodynamic status and changes at the brain tissue level. Intraoperative BOLD-CVR is feasible and safe in patients undergoing EC-IC bypass revascularization. This technique can offer immediate hemodynamic feedback on brain tissue revascularization after bypass flow augmentation surgery.
Databáze: MEDLINE