Interrelation of erectile dysfunction with obesity in patients with arterial hypertension.

Autor:	Alekseeva TA; National Medical Research Center for Cardiology of the Ministry of Health of the Russian Federation, Moscow, Russia., Shariya MA; National Medical Research Center for Cardiology of the Ministry of Health of the Russian Federation, Moscow, Russia., Gamidov SI; V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation, Moscow, Russia.; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia., Elfimova EM; National Medical Research Center for Cardiology of the Ministry of Health of the Russian Federation, Moscow, Russia., Starostin IV; National Medical Research Center for Cardiology of the Ministry of Health of the Russian Federation, Moscow, Russia., Litvin AY; National Medical Research Center for Cardiology of the Ministry of Health of the Russian Federation, Moscow, Russia., Chazova IE; National Medical Research Center for Cardiology of the Ministry of Health of the Russian Federation, Moscow, Russia.
Jazyk:	angličtina
Zdroj:	Terapevticheskii arkhiv [Ter Arkh] 2018 Dec 30; Vol. 90 (12), pp. 84-89.
DOI:	10.26442/00403660.2018.12.000013
Abstrakt:	Aim: To study the relationship between the severity of erectile dysfunction and the anthropometric parameters of obesity in patients with arterial hypertension. Materials and Methods: The study included 71 patients with different severity of erectile dysfunction, overweight and grade 1obesity and arterial hypertension. The anthropometric parameters were analyzed, the degree and characteristics of obesity were assessed according to data of multispiral computed tomography (MSCT), a preliminary assessment of erectile function was performed using the IIEF-5 questionnaire. Later the data of the questionnaire was compared with the in-depth urological study: the collection of anamnesis, examination and conduction of the pharmacodopplerography of the penis vessels. Results: Comparative analysis revealed statistically significant links between anthropometric data and the degree of abdominal obesity based on MSCT results (p<0.005), anthropometric indicators of obesity with parameters of penile arterial blood flow, as well as severity of erectile dysfunction by degree of erection and dopplerography with an estimation of the rate of penile blood flow (p<0.05). In addition, a statistically significant negative relationship between the quality of penile blood flow and the degree of arterial hypertension was revealed (p=0.02). As a result of multifactorial linear regression, it is shown that with an increased the ratio of the waist circumference to the hip circumference and a higher level of systolic blood pressure, the condition of penile arterial blood flow worsens, namely, the peak systolic velocity (PSV) decreases (β=-0.377, p=0.05; β=-0.478, p=0.02, respectively). In a comparative analysis of the subjective evaluation of erectile function according to the data of the IIEF-5 questionnaire, we showed no statistically significant association with the results of an objective examination (p=0.07).There were also no statistically significant links between objective data of erectile function and obesity parameters in MSCT. Conclusion: The combination of overweight or obesity with arterial hypertension gives ground to suspect the presence of different severity of erectile dysfunction.
Databáze:	MEDLINE
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