| Autor: |
Wang X; College of Pharmacy, Chian Pharmaceutical University, Nanjing 210009, China., Shen W; Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210009, China., Wang H; Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210009, China., Yu K; Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210009, China., Wu B; Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210009, China., Hu G; Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210009, China., Yang G; College of Pharmacy, Chian Pharmaceutical University, Nanjing 210009, China. |
| Abstrakt: |
A method was developed for the simultaneous determination of 10 perfluorinated carboxylic acid compounds in water by gas chromatography-mass spectrometry coupled with negative chemical ionization (GC-NCI-MS). Perfluorinated carboxylic acid compounds were derivatized by trifluoro- N -methyl- N -(trimethylsilyl) acetamide (MSTFA) as the trimethylsilyl derivatization reagent. The water sample was purified and enriched through a weak anion exchange solid phase extraction column and analyzed via GC-NCI-MS. The sample pretreatment, derivation and instrument conditions were optimized. The results showed that the linearity of the 10 perfluorinated carboxylic acid compounds was good in the range of 0.1-10 mg/L with correlation coefficients of 0.9956-0.9993. The limits of detection (LODs) and limits of quantification (LOQs) were 0.5-1.5 μg/L and 1.5-4.5 μg/L, respectively. The spiked recoveries of the blank samples ranged from 70.2% to 112.6% with the relative standard deviations (RSDs) between 2.1% and 14.5% ( n =6). The method is simple, sensitive, accurate and precise, and can be used to detect the 10 perfluorinated carboxylic acid compounds in water. |
