[The development of diagnostic of acute endometritis on the basis of modeling and cluster analysis of parameters of local immunity.]

Autor:	Agarkov NM; The Federal State Budget Educational Institution of Higher Education 'The South-Western State University', 305040, Kursk, Russia., Golovchenko OV; The Oblast State Budget Health Care Institution 'The Prelate Josaphat Belgorod Oblast Clinical Hospital', 308007, Belgorod, Russia., Okhotnikov OI; The Federal State Budget Educational Institution of Higher education 'The Kursk State Medical University', 305041, Kursk, Russia., Budnik IV; The Federal State Budget Educational Institution of Higher Education 'The South-Western State University', 305040, Kursk, Russia., Aksenov VV; The Federal State Budget Educational Institution of Higher Education 'The South-Western State University', 305040, Kursk, Russia., Ivanov VA; The Federal State Budget Educational Institution of Higher education 'The Kursk State Medical University', 305041, Kursk, Russia.
Jazyk:	ruština
Zdroj:	Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2018; Vol. 63 (4), pp. 239-242.
DOI:	10.18821/0869-2084-2018-63-4-239-242
Abstrakt:	The acute endometritis provoking expressed disorders of local immunity is considered as one of the prevalent complications of postnatal period and abortions. The purpose of study is to develop diagnostic of acute endometritis on the basis of applied correlation modeling and cluster analysis techniques diagnostically priority-driven immunological indices of vaginal cervical mucus. The sample included main group (154 patients with acute endometritis) and control group (103 patients with uncomplicated post-natal period). Both groups were subjected to enzyme-linked immunosorbent assay to analyze content of immunoglobulins, components of complement and lysozyme in vaginal cervical mucus. The sampling of diagnostically significant indices was implemented using correlation and cluster analysis techniques. It is established that chief diagnostic indices of local immunity in case of acute endometritis are IG M, sIg A, С4 components of complement and lysozyme. The established diagnostically significant parameters of local immunity provide development of detection of acute endometritis according less number of indices. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
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