Black and Brown: Non-neoplastic Pigmentation of the Oral Mucosa.

Autor: Rosebush MS; Louisiana State University, 1100 Florida Avenue, New Orleans, LA, 70119, USA. mroseb@lsuhsc.edu., Briody AN; Central Ohio Skin & Cancer, Inc., Westerville, OH, USA., Cordell KG; Louisiana State University, 1100 Florida Avenue, New Orleans, LA, 70119, USA.
Jazyk: angličtina
Zdroj: Head and neck pathology [Head Neck Pathol] 2019 Mar; Vol. 13 (1), pp. 47-55. Date of Electronic Publication: 2019 Jan 22.
DOI: 10.1007/s12105-018-0980-9
Abstrakt: Black and brown pigmentation of the oral mucosa can occur due to a multitude of non-neoplastic causes. Endogenous or exogenous pigments may be responsible for oral discoloration which can range from innocuous to life-threatening in nature. Physiologic, reactive, and idiopathic melanin production seen in smoker's melanosis, drug-related discolorations, melanotic macule, melanoacanthoma and systemic diseases are presented. Exogenous sources of pigmentation such as amalgam tattoo and black hairy tongue are also discussed. Determining the significance of mucosal pigmented lesions may represent a diagnostic challenge for clinicians. Biopsy is indicated whenever the source of pigmentation cannot be definitively identified based on the clinical presentation.
Databáze: MEDLINE