[Transfusion in autologous and allogenic hematopoietic stem cell transplant: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].

Autor:	Giraud C; CHU de Poitiers, service d'hématologie et de thérapie cellulaire, 2, rue de la Miletrie, 86021 Poitiers, France; Laboratoire de thérapie cellulaire EFS Nouvelle-Aquitaine, 350, avenue Jacques-Cœur, BP 482, 86012 Poitiers cedex, France. Electronic address: christine.giraud@chu-poitiers.fr., Thibert JB; Laboratoire de thérapie cellulaire EFS Bretagne, 3, rue Pierre-Jean Gineste, 35016 Rennes, France., Desbrosses Y; CHRU Jean-Minjoz, service d'hématologie, unité de soins intensifs, 3, boulevard Fleming, 25030 Besançon cedex, France., Debiol B; EFS siège, 20, avenue du stade de France, 93218 La Plaine Saint-Denis, France., Alsuliman T; CH de Boulogne-sur-Mer, allée Jacques-Monod, 62321 Boulogne-sur-Mer, France; CHRU de Lille, service des maladies du sang, 2, avenue Oscar-Lambret, 59037 Lille, France., Bardiaux L; Laboratoire immuno-hématologie EFS Toulouse-Purpan, avenue de Grande-Bretagne, BP 3210, 31027 Toulouse cedex, France., Garban F; CHU de Grenoble-Alpes, clinique d'hématologie, avenue Maquis du Grésivaudan, 38700 La Tronche, France., Huynh TNP; Institut Jules-Bordet, service d'hématologie, 1, rue Héger-Bordet, 1000 Bruxelles, Belgique., Samsonova O; Groupement hospitalier Lyon Sud, transfusion hôpital de jour hématologie, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France., Yakoub-Agha I; CHU de Lille, maladies du sang, unité d'allogreffe de CSH, 59000 Lille, France; Université de Lille 2, LIRIC, Inserm U995, 59000 Lille, France., Bruno B; Hôpital Jeanne de Flandre, CHRU de Lille, hématologie pédiatrique, unité de greffe, avenue Eugène-Avinée, 59037 Lille cedex, France.
Jazyk:	francouzština
Zdroj:	Bulletin du cancer [Bull Cancer] 2019 Jan; Vol. 106 (1S), pp. S52-S58. Date of Electronic Publication: 2019 Jan 18.
DOI:	10.1016/j.bulcan.2018.08.016
Abstrakt:	The recommendations of the French Health and Drug Safety Authorities (HAS/ANSM-Haute Autorité de santé/Agence nationale de sécurité du médicament) are known, but there are always new developments underway. With regards to CMV suppression, there is the introduction of platelet glycoprotein Ia and the Intercept (Amotosalem+UVA) inactivation method which addresses bacterial risk. The irradiation of platelets is included in the recommendations to ensure HEV-negative plasma post allograft. In terms of blood transfusion safety, these measures as well as the broader spectrum of Ia, particularly for arboviruses, are a real breakthrough. The survey conducted in clinical services and the services providing blood products for transfusion along with a literature review have shown that several improvements need to be made. The first is a reduction of transfusions of concentrated red blood cells with introduction at a threshold of 7g/dL during hospitalization of patients without a fragile clinical status. The second improvement would address transfusion of refractory thrombocytopenia, encouraging an increase in discussion between clinicians and those conducting the transfusion in order to consider different etiologies and to identify appropriate care protocols. Third would be the need for the transmission of information between the transplantation doctors and blood transfusion specialists in order to define an approach to transfusion care adapted to the patient's situation. It is important to inform and educate patients about transfusion protocols post allotransplant or autotransplant. It must be clearly communicated to patients that they should always have on their person their blood group documentation. This is especially true when receiving care for a hemopathy or an autologous transplant. If undergoing an allogeneic transplant, patients should also carry transfusion guidelines post autotransplant or post allotransplant along with the phone numbers for the stem cell transplantation department and the blood transfusion center responsible for their care. (Copyright © 2018. Published by Elsevier Masson SAS.)
Databáze:	MEDLINE
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