The impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy: a randomized controlled trial.

Autor: Paulo TRS; State University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil. thais.reis.silva@hotmail.com.; Federal University of Rio Grande do Norte, UFRN, Natal, Brazil. thais.reis.silva@hotmail.com., Rossi FE; State University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil.; Federal University of Piauí, UFPI, Teresina, Brazil., Viezel J; State University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil., Tosello GT; Federal University of São Paulo, USP, Sao Paulo, Brazil., Seidinger SC; State University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil., Simões RR; Federal University of Triângulo Mineiro, UFTM, Uberaba, Brazil., de Freitas R Jr; Federal University of Goias, UFG, Goiânia, Brazil., Freitas IF Jr; State University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil.
Jazyk: angličtina
Zdroj: Health and quality of life outcomes [Health Qual Life Outcomes] 2019 Jan 18; Vol. 17 (1), pp. 17. Date of Electronic Publication: 2019 Jan 18.
DOI: 10.1186/s12955-019-1090-4
Abstrakt: Background: This study evaluated the impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy.
Methods: Older breast cancer survivors were randomized into two groups: combined training: resistance + aerobic exercise program for nine months (n = 18) or control group (n = 18). Quality of life was assessed by the questionnaires SF36, EORTC QLQ-C30, and EORTC QLQ-BR23 at baseline, and at three, six, and nine months. The exercise group performed 40 min of resistance exercises on machines followed by 30 min of aerobic training on a treadmill 3x/wk. Repeated measures ANOVA was used to compare the groups over time.
Results: Significant time x group interactions and moderate to high effect sizes were found for physical functioning, physical health, bodily pain, general health perception, vitality, social functioning, fatigue, sleep disturbance, body image, and upset by hair loss, favoring the exercise group.
Conclusion: This study demonstrated the potential benefits and high clinical relevance of exercise programs to improve quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy.
Databáze: MEDLINE
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