Comparison of a rapid latex agglutination assay and a fluorescent-antibody technique for the detection of herpes simplex antibody.

Autor: LeBar WD; Providence Hospital, Southfield, Michigan., Resek CM, Crist AE Jr, Sautter RL
Jazyk: angličtina
Zdroj: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 1988 Sep; Vol. 11 (1), pp. 21-4.
DOI: 10.1016/0732-8893(88)90069-7
Abstrakt: A total of 202 serum specimens was tested for the presence of herpes simplex virus antibody using a premarket latex agglutination kit (Wampole) and an indirect fluorescent antibody (IFA) technique (electronucleonics). Discrepant results between the two assays were resolved using an Enzyme-linked immunosorbent assay (ELISA) procedure. The overall sensitivity of the latex was 99.2% with a specificity of 98.5%. The latex agglutination test evaluated is a viable alternative to indirect immunofluorescence for the detection of herpes simplex virus antibody in serum samples.
Databáze: MEDLINE