N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria.
| Autor: | Newton GL; Division of Biological Sciences, University of California, San Diego, San Diego, California, USA., Rawat M; Department of Biology, California State University-Fresno, Fresno, California, USA mrawat@csufresno.edu. |
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| Jazyk: | angličtina |
| Zdroj: | MBio [mBio] 2019 Jan 15; Vol. 10 (1). Date of Electronic Publication: 2019 Jan 15. |
| DOI: | 10.1128/mBio.02634-18 |
| Abstrakt: | J. Hiras, S. V. Sharma, V. Raman, R. A. J. Tinson, et al. (mBio 9:e01603-18, 2018, https://doi.org/10.1128/mBio.01603-18) report on the identification of a novel thiol, N-methyl-bacillithiol (N-Me-BSH), in the green sulfur bacterium Chlorobium tepidum In N-methyl-bacillithiol, the amine of the cysteine is methylated by a novel S -adenosylmethioneine transferase designated N-methyl-bacillithiol synthase A (NmbA). The Hiras et al. study is significant because it is the first report of the presence of N-Me-BSH in anaerobic bacteria. (Copyright © 2019 Newton and Rawat.) |
| Databáze: | MEDLINE |
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