[Control of highly toxic N-nitrosamines (N-nitrosodimethylamine and N-nitrosodiethylamine) content in baby's cereals].

Autor:	Zaytseva NV; Federal Research Center of Medical and Preventive Public Health Risk Management Technologies, Perm'., Ulanova TS; Federal Research Center of Medical and Preventive Public Health Risk Management Technologies, Perm'., Nurislamova TV; Federal Research Center of Medical and Preventive Public Health Risk Management Technologies, Perm'., Terentyev GI; Center for Hygiene and Epidemiology in the Perm Region, Perm'., Ershova KS; Federal Research Center of Medical and Preventive Public Health Risk Management Technologies, Perm'., Maltseva OA; Federal Research Center of Medical and Preventive Public Health Risk Management Technologies, Perm'.
Jazyk:	ruština
Zdroj:	Voprosy pitaniia [Vopr Pitan] 2016; Vol. 85 (3), pp. 82-90. Date of Electronic Publication: 2016 Jun 23.
DOI:	10.24411/0042-8833-2016-00038
Abstrakt:	This paper proposes gas chromatography-mass-spectrometry method for determination of N-nitrosamines (N-nitrosodimethylamine and N-nitrosodiethylamine) in dry baby cereals (milk and milk-free). According to the results of the experimental studies, the method of sample preparation has been substantiated. This is the method of distillation with superheated steam, concentration of distillate on cartridges of automatic system of solid phase extraction. Optimal conditions for chromatography-mass spectrometry analysis has been selected (GC/MS). Analysis of the cereals (milk and milkfree) on the content of N-nitrosodimethylamine and N-nitrosodiethylamine in concentration range 0.0055-0.0109 mg/kg allowed to determine high content of the determined components by the sum of N-nitrosamines in cereals' samples of different manufacturers: oatmeal with milk, buckwheat with milk, oatmeal with milk and banana, milk-free maize cereal. In the multigrain milk cereal and buckwheat with milk, peaches and apricots the content N-nitrosamines was not detected (0.0004-0.00066 mg/kg). To confirm the presence of N-nitrosamines identified in a sample of oatmeal with milk, the identification in SCAN mode has been performed. Mass-spectrum of N-nitrosodimethylamine and N-nitrosodiethylamine in examined samples were compared with massspectrums that were included in library bank of mass-spectral data NIST 08.L. (Copyright© GEOTAR-Media Publishing Group.)
Databáze:	MEDLINE
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