Metal-Free Regioselective Cross Dehydrogenative Coupling of Cyclic Ethers and Aryl Carbonyls.

Autor:	Mane KD; Chemical Engineering & Process Development Division , CSIR-National Chemical Laboratory , Dr. Homi Bhabha Road , Pune 411008 , India.; Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110 025 , India., Mukherjee A; Physical and Material Chemistry Division , CSIR-National Chemical Laboratory , Dr. Homi Bhabha Road , Pune 411008 , India.; Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110 025 , India., Vanka K; Physical and Material Chemistry Division , CSIR-National Chemical Laboratory , Dr. Homi Bhabha Road , Pune 411008 , India.; Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110 025 , India., Suryavanshi G; Chemical Engineering & Process Development Division , CSIR-National Chemical Laboratory , Dr. Homi Bhabha Road , Pune 411008 , India.; Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110 025 , India.
Jazyk:	angličtina
Zdroj:	The Journal of organic chemistry [J Org Chem] 2019 Feb 15; Vol. 84 (4), pp. 2039-2047. Date of Electronic Publication: 2019 Jan 30.
DOI:	10.1021/acs.joc.8b03048
Abstrakt:	A highly regioselective, efficient, and metal-free oxidative cross dehydrogenative coupling (CDC) of aryl carbonyls with cyclic ethers has been developed. This method offers easy access to substituted α-arylated cyclic ethers with a high functional group tolerance in good to excellent yields. The regioselectivity of this CDC reaction was confirmed by density functional theory (DFT)-based calculations.
Databáze:	MEDLINE
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