Genetic Diversity of Plasmodium vivax Causing Epidemic Malaria in the Republic of Korea.

Autor: Bahk YY; Department of Biotechnology, College of Biomedical and Health Science, Konkuk University, Chungju 27478, Korea., Kim J; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, UAB Comprehensive Diabetes Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Ahn SK; Department of Parasitology and Tropical Medicine, Inha University School of Medicine, Incheon 22212, Korea., Na BK; Department of Parasitology and Tropical Medicine and Institute of Health Sciences, Gyeongsang National University College of Medicine, Jinju 52727, Korea., Chai JY; Korea Association of Health Promotion, Seoul 07653, Korea., Kim TS; Department of Parasitology and Tropical Medicine, Inha University School of Medicine, Incheon 22212, Korea.
Jazyk: angličtina
Zdroj: The Korean journal of parasitology [Korean J Parasitol] 2018 Dec; Vol. 56 (6), pp. 545-552. Date of Electronic Publication: 2018 Dec 31.
DOI: 10.3347/kjp.2018.56.6.545
Abstrakt: Plasmodium vivax is more challenging to control and eliminate than P. falciparum due to its more asymptomatic infections with low parasite densities making diagnosis more difficult, in addition to its unique biological characteristics. The potential re-introduction of incidence cases, either through borders or via human migrations, is another major hurdle to sustained control and elimination. The Republic of Korea has experienced re-emergence of vivax malaria in 1993 but is one of the 32 malaria-eliminating countries to-date. Despite achieving successful nationwide control and elimination of vivax malaria, the evolutionary characteristics of vivax malaria isolates in the Republic of Korea have not been fully understood. In this review, we present an overview of the genetic variability of such isolates to increase understanding of the epidemiology, diversity, and dynamics of vivax populations in the Republic of Korea.
Databáze: MEDLINE