Implantation of Cardioverter-Defibrillator in Children With Long-QT Syndrome: Assessment of Indications, Efficacy, and Safety Based on 10-Year Experience.
| Autor: | Ildarova RA; Clinical Institute of Pediatrics named after Academician Y. E. Veltishev; RNIMU after N.I. Pirogov. ildarova@pedklin.ru., Shkolnikova MA, Termosesov SA |
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| Jazyk: | ruština |
| Zdroj: | Kardiologiia [Kardiologiia] 2018 Dec 25; Vol. 58 (12), pp. 52-58. Date of Electronic Publication: 2018 Dec 25. |
| DOI: | 10.18087/cardio.2018.12.10191 |
| Abstrakt: | Purpose: to assess specificities of course of the long-QT syndrome in children before and after implantation of cardioverter-defibrillator (ICD), and optimization of indications to ICD-therapy. Materials and Methods: We included in this study 48 children with long-QT syndrome from 44 unrelated families (28 boys and 20 girls), who underwent ICD implantation at the mean age 11.8±3.8 years. Mean duration of follow-up after implantation was 5.2±2.8 years. Data from these children were compared with those from 59 children of comparable age and gender with long-QT syndrome from 46 unrelated families receiving antiarrhythmic therapy (β-adrenoblockers). We assessed clinical and electrocardiographic characteristics of the disease obtained at initial visit and their dynamics thereafter. Results: Children with long-QT syndrome and ICD were mainly probands with interval QT longer than 500 ms, recurrent syncope and often history of sudden cardiac arrest requiring high doses of β-adrenoblockers for control of ventricular tachyarrhythmias. Conclusion: ICD implantation is an effective and safe method both of primary and secondary prevention of sudden cardiac death in children with long-QT syndrome. |
| Databáze: | MEDLINE |
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