Incidence of major adverse cardiac events in men wishing to continue competitive sport following percutaneous coronary intervention.

Autor: Guy JM; Centre de Réadaptation Cardio-Respiratoire de la Loire, 42100 Saint-Etienne, France., Wilson M; Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar; Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, L3 3AF, UK; Research Institute of Sport and Exercise Sciences, University of Canberra, Bruce, ACT 2601, Australia., Schnell F; CIC-IT, Inserm 1414, 35033 Rennes, France; Service de Médecine du Sport, CHU Rennes, 35033 Rennes, France; Laboratoire de Traitement du Signal et de l'Image (LTSI), Inserm UMR 1099, 35043 Rennes, France., Chevalier L; Clinique du Sport de Bordeaux-Mérignac, 33700 Mérignac, France., Verdier JC; Institut Coeur Effort Santé, 75005 Paris, France., Corone S; Cardiac Rehabilitation Department, Bligny Medical Centre, 91640 Briis-sous-Forges, France., Doutreleau S; HP2 Laboratory, University Grenoble Alpes, 38434 Echirolles, France; Inserm U1042, 33370 Grenoble, France., Kervio G; CIC-IT, Inserm 1414, 35033 Rennes, France., Carré F; CIC-IT, Inserm 1414, 35033 Rennes, France; Service de Médecine du Sport, CHU Rennes, 35033 Rennes, France; Laboratoire de Traitement du Signal et de l'Image (LTSI), Inserm UMR 1099, 35043 Rennes, France. Electronic address: francois.carre@univ-rennes1.fr.
Jazyk: angličtina
Zdroj: Archives of cardiovascular diseases [Arch Cardiovasc Dis] 2019 Apr; Vol. 112 (4), pp. 226-233. Date of Electronic Publication: 2019 Jan 03.
DOI: 10.1016/j.acvd.2018.11.008
Abstrakt: Background: The new North American guidelines for participation in competitive sport in patients with coronary artery disease (CAD) are less restrictive than previous guidelines.
Aim: To evaluate the incidence of major adverse cardiac events (MACE) in men with CAD who practise intensive physical activity after a stenting procedure. MACE included in-stent restenosis (SR), stent thrombosis (ST), new coronary stenosis (NCS), myocardial infarction, heart failure, cardiac arrest or cardiac death.
Methods: Asymptomatic men with CAD and a coronary stent who practised regular (>4h/week) sport were included in this retrospective multicentre observational study. All patients presented with left ventricular ejection fraction≥50%, no residual stenosis, and no inducible ischaemia or arrhythmias. Three groups were compared: those undertaking moderate leisure-time sport (MLS), intensive leisure-time sport (ILS) or competitive sport (CS). During follow-up, all patients had a yearly routine cardiology evaluation.
Results: A total of 108 men with CAD (57.3±9.1 years) were included: 29 MLS, 58 ILS, and 21 CS. During follow-up (57.6±46.0 months) the incidence of MACE was 15.7% (SR=5, SR+NCS=4, ST=4, NCS=4) and occurred during physical exertion in 59% of patients. ST was more frequent in the CS (n=3) than in the MLS (n=1) or ILS (n=0) groups, especially in patients with bare-metal stents.
Conclusions: The incidence of MACE was 15.7%, and only ST was significantly more frequent in CS patients than in MLS or ILS patients. Our data support the new US guidelines for exercise eligibility in men with CAD.
(Copyright © 2019 Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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