Sodium Is Detected by the OVLT to Regulate Sympathetic Tone.
Autor: | Guyenet PG; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA. Electronic address: pgg@virginia.edu. |
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Jazyk: | angličtina |
Zdroj: | Neuron [Neuron] 2019 Jan 02; Vol. 101 (1), pp. 3-5. |
DOI: | 10.1016/j.neuron.2018.12.015 |
Abstrakt: | Hypernatremia is known to elicit a rise in sympathetic tone and blood pressure. In this issue of Neuron, Nomura et al. (2018) now show that this is mediated via the organum vasculosum laminae terminalis (OVLT). Na + activates OVLT neurons via a paracrine mechanism involving sodium channel Na (Copyright © 2018 Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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