Impact of obesity and diabetes on arthritis: An update.
| Autor: | Pandey R; Department of Biochemistry, Awadhesh Pratap Singh University, Rewa, India., Kumar N; Department of Biotechnology, IMS Engineering College, Ghaziabad, India., Paroha S; Department of Biochemistry, Jawaharlal Nehru Agriculture University, Jabalpur, India., Prasad R; Amity Institute of Microbial Technology, Amity University, Noida, India., Yadav M; College of Advance Studies, Datia, India., Jain S; NIDDK, National Institutes of Health, Bethesda, USA., Yadav H; NIDDK, National Institutes of Health, Bethesda, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Health [Health (Irvine Calif)] 2013 Jan; Vol. 5 (1), pp. 143-156. Date of Electronic Publication: 2013 Jan 23. |
| DOI: | 10.4236/health.2013.51019 |
| Abstrakt: | The incidence of obesity and diabetes has been increased with alarming rate in recent years and became a common problem around the globe including developing as well as in developed countries with incalculable social costs. Obesity and type 2 diabetes are two common co-morbidities occur together. Obesity and diabetes is closely associated with many diseases, osteoarthritis, hypertension, certain form of cancer, sleep-breathing disorders and coronary heart disease. Impacts of obesity and diabetes (insulin resistance) on arthritis have been seen in patients that we associated with combination of various factors like increased availability of high- energy foods, genetic susceptibility and decreased physical activity in modern society. Arthritis is becoming pandemic around the globe and its occurrence with obesity and diabetes has been observed more common than ever. Combination of these two chronic conditions makes these diseases more vulnerable for human health. Till now very limited information is established about the pathological and mechanistic correlation among these health ailments. In this review article we aimed to survey the literature covering the influence of obesity and diabetes on arthritis pathology and tried to establish correlation with these diseases. Competing Interests: *The authors declare no conflict of interest. |
| Databáze: | MEDLINE |
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