Foundation of pediatric cancer treatment in Lao People's Democratic Republic at the Lao-Korea National Children's Hospital.

Autor: Park KD; a Department of Pediatrics , Chonbuk National University College of Medicine , Jeonju , Republic of Korea., Hong CR; b Department of Pediatrics , Seoul National University College of Medicine , Seoul , Republic of Korea., Choi JY; b Department of Pediatrics , Seoul National University College of Medicine , Seoul , Republic of Korea., Kim MS; b Department of Pediatrics , Seoul National University College of Medicine , Seoul , Republic of Korea., Yi ES; c Korea International Cooperation Agency (KOICA) , Seoul , Republic of Korea., Saysouliyo S; d Department of Pediatrics , National Children's Hospital , Vientiane , Lao Democratic People's Republic., Phongsavath K; d Department of Pediatrics , National Children's Hospital , Vientiane , Lao Democratic People's Republic., Shin HY; b Department of Pediatrics , Seoul National University College of Medicine , Seoul , Republic of Korea.
Jazyk: angličtina
Zdroj: Pediatric hematology and oncology [Pediatr Hematol Oncol] 2018 May; Vol. 35 (4), pp. 268-275. Date of Electronic Publication: 2018 Dec 31.
DOI: 10.1080/08880018.2018.1477888
Abstrakt: Aim: The Lao-Korea National Children's Hospital initiated and developed a pediatric cancer treatment program for the first time in September 2012, through education by the Lee Jong-Wook project, establishment of infrastructure by the Korea International Cooperation Agency, and cooperation of medical staff.
Material and Methods: we describe the experience of initiating and building this program by retrospectively reviewing the data from pediatric patients with cancer diagnosed at the Lao-Korea National Children's Hospital between September 2012 and December 2016.
Results: A total of 78 patients diagnosed with acute lymphoblastic leukemia (ALL) (n = 44), acute myeloid leukemia (AML) (n = 12), chronic myeloid leukemia (n = 7), lymphoma (n = 6), retinoblastoma (n = 5), Wilms tumor (n = 3), and germ cell tumor (n = 1) were included. Of the 44 patients with ALL, 40 received induction chemotherapy, and 4 refused chemotherapy. Of these 40 patients, 29 (73.6%) achieved complete remission (CR) and 9 (22.5%) died during chemotherapy. Of the 29 patients with CR, 4 completed the chemotherapy, 19 were still on chemotherapy, 4 relapsed, and 2 were deceased. Treatment was unsuccessful for all 12 patients with AML.
Conclusion: We successfully initiated the pediatric cancer care program but faced challenges associated with high mortality because of insufficient resources. We should continue our efforts to find more abandoned patients, detect cancer earlier, and reduce the overall associated mortality.
Databáze: MEDLINE
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