| Autor: |
Zhou Y; Department of Polymer Science and Engineering , University of Massachusetts Amherst , Amherst , Massachusetts 01003 , United States., Uzun SD; Department of Polymer Science and Engineering , University of Massachusetts Amherst , Amherst , Massachusetts 01003 , United States., Watkins NJ; Department of Polymer Science and Engineering , University of Massachusetts Amherst , Amherst , Massachusetts 01003 , United States., Li S; Department of Polymer Science and Engineering , University of Massachusetts Amherst , Amherst , Massachusetts 01003 , United States., Li W; Department of Polymer Science and Engineering , University of Massachusetts Amherst , Amherst , Massachusetts 01003 , United States., Briseno AL; Department of Polymer Science and Engineering , University of Massachusetts Amherst , Amherst , Massachusetts 01003 , United States., Carter KR; Department of Polymer Science and Engineering , University of Massachusetts Amherst , Amherst , Massachusetts 01003 , United States., Watkins JJ; Department of Polymer Science and Engineering , University of Massachusetts Amherst , Amherst , Massachusetts 01003 , United States. |
| Abstrakt: |
Fabrication of detection elements with ultrahigh surface area is essential for improving the sensitivity of analyte detection. Here, we report a direct patterning technique to fabricate three-dimensional CeO 2 nanoelectrode arrays for biosensor application over relatively large areas. The fabrication approach, which employs nanoimprint lithography and a CeO 2 nanoparticle-based ink, enables the direct, high-throughput patterning of nanostructures and is scalable, integrable, and of low cost. With the convenience of sequential imprinting, multilayered woodpile nanostructures with prescribed numbers of layers were achieved in a "stacked-up" architecture and were successfully fabricated over large areas. To demonstrate application as a biosensor, an enzymatic glucose sensor was developed. The sensitivity of glucose sensors can be enhanced simply by increasing the number of layers, which multiplies surface area while maintaining a constant footprint. The four-layer woodpile nanostructure of CeO 2 glucose sensor exhibited enhanced sensitivity (42.8 μA mM -1 cm -2 ) and good selectivity. This direct imprinting strategy for three-dimensional sensing architectures is potentially extendable to other electroactive materials and other sensing applications. |
