Effects of pesticide exposure on reproductivity of male groundnut farmers in Kyauk Kan village, Nyaung-U, Mandalay region, Myanmar.

Autor:	Lwin TZ; Department of Preventive and Social Medicine, Defence Services Medical Academy, Yangon, Myanmar.; Center for Risk Analysis and Health Surveillance (C-RAHS), College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand, wattasit.s@chula.ac.th., Than AA; Defence Services Orthopedics Hospital, Yangon, Myanmar., Min AZ; Military Institute of Nursing and Paramedical Sciences, Yangon, Myanmar., Robson MG; School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ, USA., Siriwong W; Center for Risk Analysis and Health Surveillance (C-RAHS), College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand, wattasit.s@chula.ac.th.; College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand, wattasit.s@chula.ac.th.
Jazyk:	angličtina
Zdroj:	Risk management and healthcare policy [Risk Manag Healthc Policy] 2018 Nov 29; Vol. 11, pp. 235-241. Date of Electronic Publication: 2018 Nov 29 (Print Publication: 2018).
DOI:	10.2147/RMHP.S175230
Abstrakt:	Introduction: Kyauk Kan village of Nyaung-U, Mandalay region, Myanmar is one of the most famous groundnut-growing zones and has been exposed to pesticides. Methods: This study design provided evaluation of within-person changes in the season across growing and nongrowing periods. A cross-sectional study was performed to identify health problems related to organophosphate pesticide (OP) exposure, to explore the protected use of this pesticide among 400 participants in the community by face-to-face interviews, and to determine the reproductive effects of OP exposure by using biomarkers of 100 male groundnut farmers aged 18-49 years. Results: The mean age of the participants was 37.5±9.45 years. Analysis revealed statistically significant differences in seminal parameters ( P <0.05 for pH, viscosity, motility, morphology, and sperm count) and in a reproductive hormonal assay ( P <0.05 in follicle-stimulating hormone and testosterone) between the growing and nongrowing periods. Blood-cholinesterase levels of plasma cholinesterase in the growing period were significantly higher than those in the nongrowing period ( P <0.05). Conclusion: Our results suggest that chronic exposure related to OP dose may reduce potential male reproductivity. Competing Interests: Disclosure The authors report no conflicts of interest in this work.
Databáze:	MEDLINE
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