Agenesis of the corpus callosum with interhemispheric cyst: clinical implications and outcome.

Autor:	Revanna KG; Neonatology, KK Women's and Children's Hospital, Singapore., Rajadurai VS; Neonatology, KK Women's and Children's Hospital, Singapore.; Duke NUS Medical School, Singapore.; NUS Yong Loo Lin School of Medicine, Singapore.; Lee Kong Chian School of Medicine, Singapore., Chandran S; Neonatology, KK Women's and Children's Hospital, Singapore.; Duke NUS Medical School, Singapore.; NUS Yong Loo Lin School of Medicine, Singapore.; Lee Kong Chian School of Medicine, Singapore.
Jazyk:	angličtina
Zdroj:	BMJ case reports [BMJ Case Rep] 2018 Dec 03; Vol. 11 (1). Date of Electronic Publication: 2018 Dec 03.
DOI:	10.1136/bcr-2018-227366
Abstrakt:	We describe two cases of agenesis of the corpus callosum (ACC) with interhemispheric cyst (IHC). Case 1: a male infant was born at 36 weeks gestation with a history of second trimester fetal ultrasound (US) scan and MRI showing ACC with IHC. His head circumference at birth and 5 months was at 90th centile. He developed infantile spasm and electroencephalogram showed hypsarrhythmia at 5 months of age. Seizures were controlled. He is under evaluation for surgical treatment. Case 2: ACC with a midline cyst was reported in the midtrimester US scan of a male infant. Subsequent fetal scans showed increasing size of the cyst. At birth, he had macrocephaly with a head circumference above 97th centile. MRI of the brain confirmed ACC with IHC. The parents refused a cystoperitoneal shunt offered. The child displayed gross neurodevelopmental delay with progressive hydrocephalus on follow-up and succumbed to aspiration pneumonia at 22 months of age. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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