There is an exception to every rule-T2-FLAIR mismatch sign in gliomas.

Autor: Johnson DR; Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. Johnson.derek1@mayo.edu., Kaufmann TJ; Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA., Patel SH; Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA, USA., Chi AS; Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA., Snuderl M; Department of Pathology, New York University School of Medicine, New York, NY, USA., Jain R; Department of Radiology, New York University School of Medicine, New York, NY, USA.; Department of Neurosurgery, New York University School of Medicine, New York, NY, USA.
Jazyk: angličtina
Zdroj: Neuroradiology [Neuroradiology] 2019 Feb; Vol. 61 (2), pp. 225-227. Date of Electronic Publication: 2018 Dec 18.
DOI: 10.1007/s00234-018-2148-4
Abstrakt: The T2-FLAIR mismatch sign, in which a low-grade glioma is hyperintense on T2-weighted MR and centrally hypointense on T2-weighted FLAIR MR, has been reported as 100% specific for IDH-mutant astrocytomas in several series. We report several cases of "false positive" T2-FLAIR mismatch sign occurring outside the context of IDH-mutant astrocytomas, predominantly in children or young adults with pediatric-type gliomas. These results suggest caution in the interpretation of the T2-FLAIR mismatch sign in the pediatric glioma population.
Databáze: MEDLINE
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