Post-thrombolysis rupture of small lenticulostriate aneurysms: A report of 2 consecutive cases.

Autor: Shi H; Department of Diagnostic Radiology, Changi General Hospital, Singapore. Electronic address: haiyuan.shi@mohh.com.sg., Wee CK; Department of Neurology, National Neuroscience Institute, Singapore., John S; Department of Neurology, National Neuroscience Institute, Singapore.
Jazyk: angličtina
Zdroj: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia [J Clin Neurosci] 2019 Feb; Vol. 60, pp. 148-150. Date of Electronic Publication: 2018 Oct 24.
DOI: 10.1016/j.jocn.2018.10.087
Abstrakt: The 2018 American Heart Association/American Stroke Association (AHA/ASA) guidelines stated that the administration of intravenous recombinant tissue-type plasminogen activator (rTPA) for acute ischaemic stroke is probably safe for patients with small (i.e. <10 mm) unruptured intracranial aneurysms. We present 2 cases of small (2 and 5 mm) lenticulostriate artery (LSA) aneurysms which ruptured immediately following rtPA infusion. The ensuing acute intracranial haemorrhages resulted in the death of one patient and severe functional impairment for the other. Given the limited literature available, the natural history of LSA aneurysms is largely unknown. This report suggests that LSA aneurysms, regardless of size, be considered separately from other conventional aneurysms as "high-risk" lesions and a contraindication to thrombolysis.
(Copyright © 2018 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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