Oral high-dose methotrexate with citrovorum factor rescue in metastastic squamous cell carcinoma of the lung.
| Autor: | Tornyos K, Faust H |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cancer [Cancer] 1978 Feb; Vol. 41 (2), pp. 400-2. |
| DOI: | 10.1002/1097-0142(197802)41:2<400::aid-cncr2820410204>3.0.co;2-d |
| Abstrakt: | Thirteen patients with metastatic squamous cell cancer of the lung were treated, in a nonrandomized study, with an oral high-dose methotrexate and citrovorum factor rescue regimen. There was some response and/or stabilization of disease for at least three months in six (46%) of 13 cases. The median survival time of the study group was double (365 vs. 180 days) that of a retrospectively matched control group. This suggests a possible therapeutic effect of this treatment program in metastatic squamous cell cancer of the lung. |
| Databáze: | MEDLINE |
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