Autor: |
Grace EM; Department of Rheumatology, McMaster University Health Sciences Centre, Chedoke McMaster Hospitals, Hamilton, Ontario, Canada., Gerecz EM, Kassam YB, Buchanan HM, Buchanan WW, Tugwell PS |
Jazyk: |
angličtina |
Zdroj: |
British journal of rheumatology [Br J Rheumatol] 1988 Oct; Vol. 27 (5), pp. 372-4. |
DOI: |
10.1093/rheumatology/27.5.372 |
Abstrakt: |
Fifty-foot walking time was used in 51 of 187 clinical therapeutic trials of antirheumatic drugs and in only 21 instances was statistical significance reached. Measurement of the 50-foot walking time showed no better performance in long-term trials of SAARDs than in short-term trials of NSAIDs. It is concluded that the 50-foot walking time is a poor outcome measure in rheumatic disease trials, despite a high intra- and interobserver reproducibility. |
Databáze: |
MEDLINE |
Externí odkaz: |
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