Contemporary Synthetic Strategies toward seco-Prezizaane Sesquiterpenes from Illicium Species.

Autor: Condakes ML; Department of Chemistry , University of California-Berkeley , Berkeley , California 94720 , United States., Novaes LFT; Department of Chemistry , University of California-Berkeley , Berkeley , California 94720 , United States., Maimone TJ; Department of Chemistry , University of California-Berkeley , Berkeley , California 94720 , United States.
Jazyk: angličtina
Zdroj: The Journal of organic chemistry [J Org Chem] 2018 Dec 21; Vol. 83 (24), pp. 14843-14852. Date of Electronic Publication: 2018 Dec 07.
DOI: 10.1021/acs.joc.8b02802
Abstrakt: Since the elucidation of the structure of anisatin in the late 1960s, sesquiterpene lactones from various Illicium species of plants have captivated synthetic chemists worldwide, resulting in a large body of synthetic work. In particular, Illicium sesquiterpenes containing the seco-prezizaane carbon framework have seen immense interest in recent years owing to desirable structural and medicinal attributes. This synopsis will focus on recently developed synthetic strategies to access these compact, highly oxidized terpenoids.
Databáze: MEDLINE