Intraoperative Portal Vein Flow > 123 mL/min Per 100 g Predicts a Better Survival of Patients After Liver Transplantation.

Autor: Marambio A; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain., Tuñon JMC; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain., Gómez LMM; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain., Martínez JMA; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain., Bellido CB; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain., Artacho GS; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain., Franco CC; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain., Pulido LB; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain., Ruiz FJP; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain., Bravo MAG; HPB and Liver Transplant Unit, University Hospital, Vírgen del Rocío, Seville, Spain. Electronic address: miagb@msn.com.
Jazyk: angličtina
Zdroj: Transplantation proceedings [Transplant Proc] 2018 Dec; Vol. 50 (10), pp. 3582-3586. Date of Electronic Publication: 2018 Jun 30.
DOI: 10.1016/j.transproceed.2018.06.032
Abstrakt: Objective: To assess the importance of intraoperative portal vein flow measurement during liver transplantation in relation to postoperative complications and graft and patient survival.
Materials and Methods: Retrospective review including 291 patients who had all the information and covering a period of 10 years (2007-2017). Using a receiver operating characteristic curve, a cut-off point that would have the greatest impact on the probability of being alive at 5 years was established. In relation to this value, 2 groups were formed (low and high flow) and demographic variables, intraoperative variables, postoperative complications, and graft and patient survival were compared.
Results: A portal flow of 123 mL/min per100 g of liver tissue was established (area under the curve = 0.58), obtaining a low-flow (n = 129) and a high-flow group (n = 162). The 2 groups were similar in their preoperative characteristics, except for a higher proportion of preoperative ascites, a higher Model for End-Stage Liver Disease score and a lower weight of donors in the high-flow group. The arterial and portal flows were significantly higher in the high-flow group. In the postoperative period, the high-flow group presented a higher rate of ascites. The 5-year survival rate of patients was significantly higher in the high-flow group (76% vs 84%, P = .03).
Conclusions: Patients undergoing liver transplantation with an intraoperative portal vein flow measurement >123 mL/min per 100 g present a greater 5-year survival rate.
(Copyright © 2018 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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