A potential role for SMAD9 in goose follicular selection through regulation of mRNA levels of luteinizing hormone receptor.
Autor: | Yu D; College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, Wuhu, Anhui, PR China; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an, Anhui, PR China., Zhang L; College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, Wuhu, Anhui, PR China., Wang H; College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, Wuhu, Anhui, PR China., Chen F; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, PR China., Chen J; College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, Wuhu, Anhui, PR China., Zhang Z; College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, Wuhu, Anhui, PR China., Li J; College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, Wuhu, Anhui, PR China., Xing C; College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, Wuhu, Anhui, PR China., Li H; Department of Biochemistry and Molecular Biology, Augusta University, Augusta, USA., Li J; College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, Wuhu, Anhui, PR China. Electronic address: lijunplant@163.com., Cai Y; College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, Wuhu, Anhui, PR China; College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, PR China. Electronic address: ycai@njau.edu.cn. |
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Jazyk: | angličtina |
Zdroj: | Theriogenology [Theriogenology] 2019 Sep 01; Vol. 135, pp. 204-212. Date of Electronic Publication: 2018 Nov 22. |
DOI: | 10.1016/j.theriogenology.2018.11.022 |
Abstrakt: | The egg production of poultry depends on follicular development and selection. Nonetheless, the mechanism underlying the priority of selecting of hierarchical follicles is completely unknown. SMAD9 is one of the important transcription factors in the BMP/SMAD pathway and is involved in goose follicular initiation. To identify its potential role in determination of the goose follicle hierarchy, we used BMP type I receptor inhibitor LDN-193189 both in vivo and in vitro and found that SMAD9 mRNA expression decreased in the presence of LDN-193189. While the level of SMAD9 mRNA decreased after treatment with LDN-193189, we found that the egg production (7.08 eggs per bird per year) of the animals increased, estradiol (E (Copyright © 2018. Published by Elsevier Inc.) |
Databáze: | MEDLINE |
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