Anticholinergic Toxicity
| Autor: | Broderick ED; Campbell Un, Southeastern Regional MC, Metheny H; Integris Southwest Medical Center, Crosby B; Southeastern Regional Medical Center |
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| Jazyk: | angličtina |
| Zdroj: | 2022 Jan. |
| Abstrakt: | Anticholinergic toxicity is common in the emergency department but rarely fatal. According to the 2015 annual American Association of Poison Control Centers (AAPCC) report, there were just under 14,000 exposures reported to poison control centers that year, none of which lead to mortality. However, in prior years, up to 51 cases have been reported as deadly. Overdoses of compounds with anticholinergic activity can be accidental or intentional. This is an important topic as anticholinergics are readily accessible, and many medications have anticholinergic side effects. The mechanism of action of anticholinergic compounds is the antagonization of the neurotransmitter acetylcholine. Many pharmaceuticals and substances found in plants contain anticholinergic activity. (Copyright © 2022, StatPearls Publishing LLC.) |
| Databáze: | MEDLINE |
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