The Predictive Ability of Pre-Operative Magnetic Resonance Imaging to Detect Pathological Outcomes in Prostate Cancer

Autor:	Nason GJ; Department of Urology, Cork University Hospital, Wilton, Cork, Ireland, Selvarajah L; Department of Radiology, Cork University Hospital, Wilton, Cork, Ireland, O’Connor EM; Department of Urology, Cork University Hospital, Wilton, Cork, Ireland, O’Kelly J; Department of Urology, Cork University Hospital, Wilton, Cork, Ireland, Considine SW; Department of Urology, Cork University Hospital, Wilton, Cork, Ireland, Moss B; Department of Urology, Cork University Hospital, Wilton, Cork, Ireland, MacMahon D; Department of Urology, University Hospital Waterford, Waterford, Ireland, Heneghan J; Department of Radiology, University Hospital Waterford, Waterford, Ireland, Meyer N; Department of Histopathology, Cork University Hospital, Wilton, Cork, Ireland, Buckley J; Department of Radiology, Cork University Hospital, Wilton, Cork, Ireland, O’Regan K; Department of Radiology, Cork University Hospital, Wilton, Cork, Ireland, O’Brien MF; Department of Urology, Cork University Hospital, Wilton, Cork, Ireland; Department of Urology, University Hospital Waterford, Waterford, Ireland
Jazyk:	angličtina
Zdroj:	Irish medical journal [Ir Med J] 2018 Aug 13; Vol. 111 (7), pp. 790. Date of Electronic Publication: 2018 Aug 13.
Abstrakt:	Aims Accurate preoperative knowledge of tumour stage is important in preoperative planning at radical prostatectomy (RP). The aim of this study was to assess the predictive ability of multiparametric MRI for detecting pathological outcomes. Methods A retrospective review was performed of all patients who underwent RP over a 4 year period. Results Preoperative MRI was reported as showing T3 or T4 disease in 26(17.9%) out of 145 patients undergoing RP. Of these, 10(6.9%) had ECE (extra-capsular extension) and 1(0.7%) had SVI (seminal vesicle invasion) on final histology. The sensitivity and specificity of MRI for detecting ECE were 27.3% and 87.6%, respectively. The sensitivity and specificity of MRI for detecting SVI were 11.1% and 97.8%, respectively. The positive predictive values for determining ECE and SVI were 45.5% and 25%, respectively and negative predictive values were 75.9% and 94.4%. Conclusion MRI has good specificity but poor and heterogeneous sensitivity for predicting T3 disease in RP specimen. Competing Interests: There are no conflicts of interest to report.
Databáze:	MEDLINE
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