Radiotherapy and pasireotide treatment of a growth hormone producing pituitary tumor in a diabetic dog.

Autor:	Zublena F; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., Tamborini A; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., Mooney CT; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., North SM; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., Lobacz MA; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., Andrew D; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., Woolhead V; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., Covey H; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., Schmid HA; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., Church DB; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid)., Niessen SJM; Southfields Veterinary Specialists, formerly VRCC, Laindon, United Kingdom (Zublena, Tamborini, North, Lobacz); SeersCroft, North Norsham, United Kingdom (Andrew); University Veterinary Hospital, Dublin, Ireland (Mooney); Department of Clinical Science and Services, The Royal Veterinary College, Herts, United Kingdom (Woolhead, Covey, Church, Niessen); Novartis Institutes for BioMedical Research, Oncology Research, Novartis Pharma AG, Basel, Switzerland (Schmid).
Jazyk:	angličtina
Zdroj:	The Canadian veterinary journal = La revue veterinaire canadienne [Can Vet J] 2018 Oct; Vol. 59 (10), pp. 1089-1093.
Abstrakt:	An 8-year-old castrated male border terrier dog was diagnosed with acromegaly resulting from a growth hormone secreting pituitary tumor. Sixteen daily fractions of radiation therapy were delivered followed, approximately 1 year later, by administration of pasireotide. The aforementioned treatment was considered effective and should be further evaluated in similar cases. Competing Interests: Conflict of interest declaration: Dr. Herbert A. Schmid is employed by Novartis Pharma AG, Basel which manufactures and markets pasireotide for the treatment of hyperadrenocorticism and hypersomatotropism in humans.
Databáze:	MEDLINE
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