Evaluation of the sintering temperature on the mechanical behavior of β-tricalcium phosphate/calcium silicate scaffolds obtained by gelcasting method.

Autor: de Siqueira L; Laboratory of Bioceramics (BIOCERAM), Institute of Science and Technology - ICT, Federal University of São Paulo - UNIFESP, 12231-280 São José dos Campos, SP, Brazil., de Paula CG; Laboratory of Bioceramics (BIOCERAM), Institute of Science and Technology - ICT, Federal University of São Paulo - UNIFESP, 12231-280 São José dos Campos, SP, Brazil., Gouveia RF; National Nanotechnology Laboratory (LNNANO), National Center for Energy and Materials (CNPEM), P.O. Box 6192, 13083-970 Campinas, SP, Brazil., Motisuke M; Laboratory of Bioceramics (BIOCERAM), Institute of Science and Technology - ICT, Federal University of São Paulo - UNIFESP, 12231-280 São José dos Campos, SP, Brazil., de Sousa Trichês E; Laboratory of Bioceramics (BIOCERAM), Institute of Science and Technology - ICT, Federal University of São Paulo - UNIFESP, 12231-280 São José dos Campos, SP, Brazil. Electronic address: eliandra.sousa@unifesp.br.
Jazyk: angličtina
Zdroj: Journal of the mechanical behavior of biomedical materials [J Mech Behav Biomed Mater] 2019 Feb; Vol. 90, pp. 635-643. Date of Electronic Publication: 2018 Nov 17.
DOI: 10.1016/j.jmbbm.2018.11.014
Abstrakt: Scaffolds have been studied during the last decades as an alternative method to repair tissues. They are porous structures that act as a substrate for cellular growth, proliferation and differentiation. In this study, scaffolds of β-tricalcium phosphate with calcium silicate fibers were prepared by gel casting method in order to be characterized and validated as a better choice for bone tissue treatment. Gel-casting led to scaffolds with high porosity (84%) and pores sizes varying from 160 to 500 µm, which is an important factor for the neovascularization of the growing tissue. Biocompatible and bioactive calcium silicate fibers, which can be successfully produced by molten salt method, were added into the scaffolds as a manner to improve its mechanical resistance and bioactivity. The addition of 5 wt% of calcium silicate fibers associated with a higher sintering temperature (1300 °C) increased by 64.6% the compressive strength of the scaffold and it has also led to the formation of a dense and uniform apatite layer after biomineralization assessment.
(Copyright © 2018 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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