The Effect of Acute Glutamine Supplementation on Markers of Inflammation and Fatigue During Consecutive Days of Simulated Wildland Firefighting.
| Autor: | Nava RC; Department of Health, Exercise, and Sport Science, College of Education, Exercise Physiology Lab, Johnson Center B143 MSC04 2610, University of New Mexico, Albuquerque, New Mexico., Zuhl MN, Moriarty TA, Amorim FT, Bourbeau KC, Welch AM, McCormick JJ, King KE, Mermier CM |
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| Jazyk: | angličtina |
| Zdroj: | Journal of occupational and environmental medicine [J Occup Environ Med] 2019 Feb; Vol. 61 (2), pp. e33-e42. |
| DOI: | 10.1097/JOM.0000000000001507 |
| Abstrakt: | Objective: To examine the effect of oral glutamine supplementation on inflammation and fatigue during and after simulated wildland firefighting (WLFF) tasks in hot conditions over 2 consecutive days. Methods: Eleven men and women ingested a glutamine supplement or a placebo before and after simulated wildland firefighting in an environmental chamber (38 °C, 35% relative humidity). Subjective fatigue, markers of inflammation, and cellular stress were measured pre, post and 4 hours post-exercise on both days. Results: Gastrointestinal damage, subjective fatigue, and ratings of perceived exertion were lower after glutamine supplementation compared with placebo. Heat shock protein 70 (HSP70) and nuclear factor kappa-inhibitor alpha (IκBα) levels were higher on both days of the glutamine trial compared with placebo. Conclusions: Glutamine supplementation may improve recovery after fire suppression in WLFFs. This may result from the upregulation of HSP70 which inhibits inflammation and protects against gastrointestinal (GI) barrier damage. |
| Databáze: | MEDLINE |
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