Mammary Paget's Disease of the Nipple: Relatively Common but Still Unknown to Many.

Autor: Ooi PS; Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, Malaysia., Draman N; Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, Malaysia., Yusoff SSM; Department of Family Medicine, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, Malaysia., Zain WZW; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, Malaysia., Ganasagaran D; Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, Malaysia., Chua HH; Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, Malaysia.
Jazyk: angličtina
Zdroj: Korean journal of family medicine [Korean J Fam Med] 2019 Jul; Vol. 40 (4), pp. 269-272. Date of Electronic Publication: 2018 Nov 29.
DOI: 10.4082/kjfm.17.0143
Abstrakt: Mammary Paget's disease is clinically defined as skin inflammation of the nipple area and is an adenocarcinoma of the epidermis of the nipple. The pathogenesis of mammary Paget's disease is relatively unknown; nonetheless, there are two popular theories that support the underlying carcinoma and de novo carcinogenesis. For the attending medical practitioner, mammary Paget's disease poses a diagnostic and therapeutic dilemma, especially in the absence of a clinically palpable breast mass. We report a rare case of a 48-year-old Malay woman who presented at Hospital Universiti Sains Malaysia, Kelantan, Malaysia with the symptom of skin erosion on the left nipple and unresponsiveness to multiple topical treatments. A full evaluation and assessment of the patient were conducted, and mammary Paget's disease was diagnosed.
Databáze: MEDLINE