Hepatocellular carcinoma in otherwise sonographically normal liver.

Autor: Naganuma H; Department of Gastroenterology, Yokote Municipal Hospital, Yokote, Akita Prefecture, Japan., Ishida H; Department of Gastroenterology, Akita Red Cross Hospital, Akita, Akita Prefecture, Japan., Ogawa M; Department of Gastroenterology and Hepatology, Nihon University, Chiyoda, Tokyo, Japan., Sato T; Department of Surgery, Akita Municipal Hospital, Akita Prefecture, Japan., Sageshima M; Department of Pathology, Akita Municipal Hospital, Akita Prefecture, Japan., Suzuki K; Department of Gastroenterology, Yamagata Prefectural Central Hospital, Yamagata, Yamagata Prefecture, Japan., Ohyama Y; Department of Clinical Laboratory, Akita Kousei Medical Hospital, Akita, Akita Prefecture, Japan.
Jazyk: angličtina
Zdroj: Journal of clinical ultrasound : JCU [J Clin Ultrasound] 2019 Jul; Vol. 47 (6), pp. 325-330. Date of Electronic Publication: 2018 Nov 28.
DOI: 10.1002/jcu.22677
Abstrakt: Purpose: Hepatocellular carcinoma (HCC) on normal liver is very rare. The goal of this study was to determine the clinical manifestations and the role of ultrasonography (US) in the diagnosis of HCC arising in normal liver.
Methods: The clinical data and US findings in 12 cases of surgically resected HCC in normal liver were retrospectively analyzed.
Results: The patients were asymptomatic, had no hepatocarcinogenic factor, and hepatic function tests were almost normal in most cases. HCCs were large, encapsulated, and solitary, and there were predominantly well-differentiated or moderately differentiated in most cases. US showed a hypoechoic rim and lateral shadowing, suggestive of peritumoral capsule formation, and on contrast-enhanced US (CEUS), the tumor was hyperenhanced in arterial phase and washed out in postvascular phase, revealing typical HCC findings.
Conclusions: US raises suspicion of HCC by showing lateral shadowing on grayscale ultrasound and hypervascularity on CEUS of the lesion.
(© 2018 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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