Role Of Radiosurgery In Arteriovenous Malformations.

Autor: Ahmed SI; Abbasi Shaheed Hospital, Karachi, Pakistan., Javed G; Aga Khan University Hospital, Karachi, Pakistan., Uneeb SN; Liaquat National Medical College, Karachi, Pakistan., Bareeqa SB; Jinnah Medical and Dental College, Karachi, Pakistan., Haider M; Bahria Medical University, Karachi, Pakistan., Samar SS; Jinnah Sindh Medical University, Karachi, Pakistan., Ans AH; Services Institute of Medical Science, Lahore, Pakistan., Shera MT; King Edward Medical University, Lahore-Pakistan.
Jazyk: angličtina
Zdroj: Journal of Ayub Medical College, Abbottabad : JAMC [J Ayub Med Coll Abbottabad] 2018 Jul-Sep; Vol. 30 (3), pp. 449-457.
Abstrakt: Background: Intracranial arteriovenous malformations (AVMs) consist of an abnormal nidus of blood vessels that shunt blood directly from an artery to a vein and thereby bypass an intervening capillary bed. AVMs may be found as an incidental finding. They may be associated with intracranial haemorrhage, seizures, headaches or neurological deficits. There are different treatment options for AVM. These include observation, microsurgery, Stereotactic radio surgery (SRS), endovascular embolization and intensity modulated radiotherapy (IMRT).
Methods: Data was collected using searching engines like Pubmed, Google scholar, Embase, Cinahl and Medline. MeSH and Non-MeSH terms were used like Arterio-venous malformations, microsurgery, endovascular embolization.
Results: Multiple interventional radiosurgical techniques have been introduced in recent years. The most effective and least risk-associated methods are Stereotactic radiosurgery, Microsurgery, Embolization and Intensity modulated radiotherapy (IMRT). However, the outcome of such treatment modalities depends upon Site of malformation, grade of AVM, patient's age/gender, dose and volume of radiosurgery. Digital substraction angiography (DSA) and MR angiography (MRA) are most suitable methods for the follow-up of AVMs.
Conclusions: Stereotactic radiosurgery is the most suitable technique for AVMs considering the good prognosis and the risks associated with this procedure. However, large AVMs require multidisciplinary approach for better results.
Databáze: MEDLINE