Structural snapshots of OxyR reveal the peroxidatic mechanism of H 2 O 2 sensing.
Autor: | Pedre B; Center for Structural Biology, Vlaams Instituut voor Biotechnologie-Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050 Brussels, Belgium., Young D; Center for Structural Biology, Vlaams Instituut voor Biotechnologie-Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050 Brussels, Belgium., Charlier D; Research Group of Microbiology, Vrije Universiteit Brussel, B-1050 Brussels, Belgium., Mourenza Á; Department of Molecular Biology, Area of Microbiology, University of León, 24071 León, Spain., Rosado LA; Center for Structural Biology, Vlaams Instituut voor Biotechnologie-Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050 Brussels, Belgium., Marcos-Pascual L; Department of Molecular Biology, Area of Microbiology, University of León, 24071 León, Spain., Wahni K; Center for Structural Biology, Vlaams Instituut voor Biotechnologie-Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050 Brussels, Belgium., Martens E; Center for Structural Biology, Vlaams Instituut voor Biotechnologie-Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050 Brussels, Belgium., G de la Rubia A; Department of Molecular Biology, Area of Microbiology, University of León, 24071 León, Spain., Belousov VV; Department of Metabolism and Redox Biology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow 117997, Russia.; Institute of Translational Medicine, Pirogov Russian National Research Medical University, Moscow 117997, Russia.; Institute for Cardiovascular Physiology, Georg August University Göttingen, 37073 Göttingen, Germany., Mateos LM; Department of Molecular Biology, Area of Microbiology, University of León, 24071 León, Spain; luis.mateos@unileon.es joris.messens@vib-vub.be., Messens J; Center for Structural Biology, Vlaams Instituut voor Biotechnologie-Vrije Universiteit Brussel, B-1050 Brussels, Belgium; luis.mateos@unileon.es joris.messens@vib-vub.be.; Brussels Center for Redox Biology, Vrije Universiteit Brussel, B-1050 Brussels, Belgium.; Structural Biology Brussels, Vrije Universiteit Brussel, B-1050 Brussels, Belgium. |
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Jazyk: | angličtina |
Zdroj: | Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Dec 11; Vol. 115 (50), pp. E11623-E11632. Date of Electronic Publication: 2018 Nov 21. |
DOI: | 10.1073/pnas.1807954115 |
Abstrakt: | Hydrogen peroxide (H Competing Interests: The authors declare no conflict of interest. (Copyright © 2018 the Author(s). Published by PNAS.) |
Databáze: | MEDLINE |
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